The haemagglutinin gene of bovine-origin H5N1 influenza viruses currently retains receptor-binding and pH-fusion characteristics of avian host phenotype
in 'Emerging Microbes & Infections'
By jiayun Yang, Mehnaz Quereshi, Reddy Kolli, Thomas P. Peacock, Jean-Remy Sadeyen, Toby Carter, Samuel Richardson, Rebecca Daines, Wendy S. Barclay, Ian Brown, Munir Iqbal
Published on 27/01/2025
This study compared the HA genes of cattle and goat H5N1 viruses with the dominant avian-origin clade 2.3.4.4b H5N1 in the UK, focusing on receptor binding, pH fusion and thermostability.