Research publication

Immune escape adaptive mutations in the H7N9 avian influenza hemagglutinin protein increase virus replication fitness and decrease pandemic potential

in 'Journal of Virology'

By Munir Iqbal, Pengxiang Chang, Joshua E. Sealy, Jean-Remy Sadeyen, Sushant Bhat, Deimante Lukosaityte, Yipeng Sun

Published on 23/07/2020

This paper shows how mutations in the H7N9 bird flu virus increase its replication rate and stability in avian cells, but reduce its preference for infecting human cells.

Read the Open Access paper

Graphical abstract of Munir et al's paper in JVI — Graphical abstract of Munir et al’s paper in JVI

Theme

Avian influenza
Disease transmission
Host/disease evolution

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Partner